One Piece: Tobidase Kaizoku-dan! is a video game based on the One Piece anime and manga series. While the Strawhats are relaxing on the Going Merry they are attacked by an unknown vessel. Scattering the crew leaving only Usopp onboard the Going Merry. In the game you take control of a young gang of pirates called the Gejitsu Pirates. Together with Usopp they go on a quest to locate the other Strawhats and hunt down the pirate Skullface who is responsible for the attack.
In most part of the game the player will sail around with the Going Merry and visit locations from the series. During the sailing the player will encounter hostile pirate crews. Battles against these pirates take place in turn based battles in which the player controls the three Gejitsu Pirates (Yuta, Reika and Ryuji). Sometimes enemy ships have to be fought in first person navel battles.