Kemono Friends 3 follows up after the end of the second season of the anime. It takes place in a surreal nature preserve called Japari Park, full of animal/human hybrids known as Friends. While humans and Friends once coexisted there, humanity has long since evacuated and Friends now live simple, happy lives alone accompanied by small robots called Lucky Beasts.
In this game a new human is escorted to the Japari Security and Research Team (JSRT) by a Lucky Beast, where they encounter both new and old Friends. Gameplay flows in traditional Japanese RPG style; story-based missions are punctuated by traditional turn-based combat, where parties of up to five Friends take on various enemies.